The handshake position of vertical mice keeps the wrist from bending as much to the side while the forearm also turns inward to a lesser degree (Schmid, et al., 2015). This means that muscle activity in the forearm is less than it would be when using a conventional mouse (Quemelo & Vieira, 2013).
Research has shown that the use of a vertical joystick mouse ensures a faster recovery from forearm, wrist and hand complaints (Aarås, et al., 2001).